Active Posts in Deterministic Lateral Displacement Devices

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Tuning Deterministic Lateral Displacement Devices Using Dielectrophoresis

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Improved performance of deterministic lateral displacement arrays with triangular posts

Deterministic lateral displacement arrays have shown great promise for size-based particle analysis and purification in medicine and biology. Here, we demonstrate that the use of an array of triangular rather than circular posts significantly enhances the performance of these devices by reducing clogging, lowering hydrostatic pressure requirements, and increasing the range of displacement chara...

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Multidirectional sorting modes in deterministic lateral displacement devices.

Deterministic lateral displacement (DLD) devices separate micrometer-scale particles in solution based on their size using a laminar microfluidic flow in an array of obstacles. We investigate array geometries with rational row-shift fractions in DLD devices by use of a simple model including both advection and diffusion. Our model predicts multidirectional sorting modes that could be experiment...

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Separation of deformable particles in deterministic lateral displacement devices.

Using numerical simulations, we study the separation of deformable bodies, such as capsules, vesicles, and cells, in deterministic lateral displacement devices, also known as bump arrays. These arrays comprise regular rows of obstacles such as micropillars whose arrangements are shifted between adjacent rows by a fixed amount. We show that, in addition to the zigzag and laterally displaced traj...

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Fractionation by shape in deterministic lateral displacement microfluidic devices

The ability to use microfluidic systems to fractionate a mixture of suspended particles based on their shape could lead to important applications. In the case of bioparticles, for example, shape is an important factor used to identify and characterize them. In fact, cell morphology has long been used in clinical diagnosis and it is also a marker of cell cycle (Sugaya et al. 2011; Beech et al. 2...

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ژورنال

عنوان ژورنال: Advanced Materials Technologies

سال: 2019

ISSN: 2365-709X,2365-709X

DOI: 10.1002/admt.201900339